CLINICAL TRIALS
Blood Transfus. 2023 Nov 3
Multi-component cord blood banking: a proof-of-concept international exercise
Dinara Samarkanova, Margarita Codinach, Tiziana Montemurro, Larysa Mykhailova, Giuseppa Tancredi, Pasquale Gallerano, Panagiotis Mallis, Efstathios Michalopoulos, Liam Wynn, Javier Calvo, Oscar M Pello, Ioanna Gontica, Paolo Rebulla, Sergio Querol, MultiCord12 Study Group
Affiliations
- Banc de Sang i Teixits, Barcelona, Spain.
- Transfusion medicine study group, Vall de Hebron, Barcelona, Spain.
- Department of Transfusion Medicine and Hematology, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy.
- Sciacca Cord Blood Bank, Sciacca, Italy.
- Hellenic Cord Blood Bank, Biomedical Research Foundation Academy of Athens, Athens, Greece.
- Anthony Nolan Cell Therapy Centre, Nottingham, UK.
- Banc de Sang i Teixits de les Illes Balears, Cell Therapy and Tissue Engineering Group (TERCIT), Balearic Islands Health Research Institut (IdISBa), Palma, Spain.
- HSC Processing and Cell Therapy Unit, Marques de Valdecilla Foundation, Santander, Spain.
- Hematologic Neoplasms and Hematopoietic Stem Cells Transplantation Group, Marques de Valdecilla Research Institute, Santander, Spain.
- Public Cord Blood Bank of Crete, Department of Hematology, University Hospital of Heraklion, Crete, Greece.
- Hemopoiesis Research Laboratory, School of Medicine, University of Crete, Crete, Greece.
PMID: 37146297
PMCID: PMC10645353
DOI: 10.2450/BloodTransfus.492
Front Pediatr. 2023 Oct 12
Effect of autologous umbilical cord blood transfusion in the development of retinopathy of prematurity: randomized clinical trial – study protocol
Laura Torrejon-Rodriguez , Alejandro Pinilla-Gonzalez , Inmaculada Lara Cantón , Abel Albiach-Delgado , Mari Merce Cascant-Vilaplana , María Cernada , Julia Kuligowski , Maria Pilar Solves Alcaina , Inés Gómez , Maximo Vento , Marta Aguar Carrascosa
Affiliations
- Department of Neonatology, Instituto de Investigación Sanitaria La Fe (IISLAFE), Valencia, Spain.
- Neonatal Research Group, Hospital Universitario y Politécnico La Fe (HULAFE), Valencia, Spain.
- Department of Hematology, Hospital Universitario y Politécnico La Fe (HULAFE), Valencia, Spain.
PMID: 37900679
PMCID: PMC10602804
DOI: 10.3389/fped.2023.1269797
Front Cell Dev Biol. 2022 Jan 4.
Recycling Apparent Waste Into Biologicals: The Case of Umbilical Cord Blood in Italy and Spain
Paolo Rebulla, Sergio Querol, Simonetta Pupella, Daniele Prati, Joaquin Delgadillo, and Vincenzo De Angelis
Affiliations
- Department of Transfusion Medicine and Hematology, Foundation IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy.
- Banc de Sang I Teixits, Barcelona, Spain.
- Centro Nazionale Sangue, Rome, Italy.
PMID: 35059402
PMCID: PMC8763965
DOI: 10.3389/fcell.2021.812038
J Pediatr Surg. 2021 Nov 5.
Fetal hemoglobin levels in premature newborns. Should we reconsider transfusion of adult donor blood?
Amelia E Gavulic, Danielle Dougherty, Shih-Hon Li, Alissa R Carver, Jennifer R Bermick, George B Mychaliska, Ronald B Hirschl, Erin E Perrone
Affiliations
- University of Michigan, Michigan Medicine, Department of Surgery, Section of Pediatric Surgery, Ann Arbor, MI, USA.
- University of Michigan, Michigan Medicine, Department of Surgery, Section of Pediatric Surgery, Ann Arbor, MI, USA; University of Michigan, Fetal Diagnosis and Treatment Center, Ann Arbor, MI, USA.
- University of Michigan, Michigan Medicine, Department of Pathology, Ann Arbor, MI, USA.
- University of Michigan, Fetal Diagnosis and Treatment Center, Ann Arbor, MI, USA; University of Michigan, Michigan Medicine, Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Ann Arbor, MI, USA.
- University of Michigan, Fetal Diagnosis and Treatment Center, Ann Arbor, MI, USA; University of Michigan, Michigan Medicine, Department of Pediatrics, Neonatal-Perinatal Medicine Division, Ann Arbor, MI, USA.
PMID: 34052004
DOI: 10.1016/j.jpedsurg.2021.04.018
Multicentre Study > Blood Transfus. 2020 Oct 9.
Clinical evaluation of allogeneic eye drops from cord blood platelet lysate
Dinara Samarkanova , Sara Martin , Laia Bisbe , Javier Puig , Marta Calatayud-Pinuaga , Luciano Rodriguez , Carmen Azqueta , Ruth Coll , Ricardo Casaroli-Marano , Alejandro Madrigal , Paolo Rebulla , Sergio Querol , on behalf of the Barcelona CBED Study Group
Affiliations
- Banc de Sang I Teixits, Barcelona, Spain.
- Transfusional Medicine Research Group, Vall d’Hebron Research Institute (VHIR), Barcelona, Spain.
- Department of Medicine, Autonomous University of Barcelona (UAB), Barcelona, Spain.
- Department of Ophthalmology, Vall d’Hebron University Hospital, Barcelona, Spain.
- Quironsalud Cataract & Lasik Eye Surgery Hospital Dubai, Dubai, United Arab Emirates.
- Department of Surgery, School of Medicine & Hospital Clinic of Barcelona, University of Barcelona, Barcelona, Spain.
- “Anthony Nolan” Research Institute, London, United Kingdom.
- Department of Transfusion Medicine and Haematology, IRCCS, Foundation Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy.
PMID: 33085593
PMCID: PMC8297669
DOI: 10.2450/2020.0130-20
Randomized Controlled Trial > Semin Vasc Surg. 2017 Dec 30.
Efficacy of cord blood platelet gel application for enhancing diabetic foot ulcer healing after lower limb revascularization
Pietro Volpe, Daniela Marcuccio, Giuseppe Stilo, Antonino Alberti, Giovanni Foti, Alberto Volpe, Domenica Princi, Rosangela Surace, Giulia Pucci, Mafalda Massara
Affiliations
- Unit of Vascular Surgery, Bianchi-Melacrino-Morelli Hospital, Reggio Calabria, Italy.
- Calabria Cord Blood Bank, Service of Immunohaematology and Transfusion Medicine, Bianchi-Melacrino-Morelli Hospital, Reggio Calabria, Italy.
- University Campus Biomedico of Rome, Rome, Italy.
- Unit of Vascular and Endovascular Surgery, SS Annunziata Hospital, Taranto, Italy.
PMID: 29793677
DOI: 10.1053/j.semvascsurg.2017.12.001
Multicentre Study > Blood Transfus. 2016 Jan 14.
Multicentre standardisation of a clinical grade procedure for the preparation of allogeneic platelet concentrates from umbilical cord blood
Paolo Rebulla, Simonetta Pupella, Michele Santodirocco, Noemi Greppi, Ida Villanova, Marina Buzzi, Nicola De Fazio, Giuliano Grazzini, Italian Cord Blood Platelet Gel Study Group
Affiliations
- Blood Transfusion Centre, Foundation Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy.
- Italian National Blood Centre, National Institute of Health, Rome, Italy.
- Puglia Cord Blood Bank, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy.
- Pescara Cord Blood Bank, UOSD Tissue and Biobank, Department of Haematology, Transfusion Medicine and Biotechnologies, Ospedale Civile dello Spirito Santo, Pescara, Italy.
- Emilia Romagna Cord Blood Bank, Immunohaematology and Transfusion Medicine, Policlinico S. Orsola-Malpighi, Bologna, Italy.
- Organ and Tissue Transplant Unit, Foundation Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy.
PMID: 26509822
PMCID: PMC4731342
DOI: 10.2450/2015.0122-15
Case Reports > Blood Transfus. 2015 Jan 13.
Preliminary evaluation of cord blood platelet gel for the treatment of skin lesions in children with dystrophic epidermolysis bullosa
Gianluca Tadini, Sophie Guez, Lidia Pezzani, Maurizio Marconi, Noemi Greppi, Francesca Manzoni, Paolo Rebulla, Susanna Esposito
Affiliations
- Paediatric Dermatology Unit, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy Paediatric Highly Intensive Care Unit, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy.
- Paediatric Highly Intensive Care Unit, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy.
- Blood Transfusion Unit, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy.
PMID: 25369602
PMCID: PMC4317102
DOI: 10.2450/2014.0160-14
Case Reports > BMJ Case Rep. 2015 Jan 8.
Cord blood platelet gel treatment of dystrophic recessive epidermolysis bullosa
Gianluca Tadini, Lidia Pezzani, Stefano Ghirardello, Paolo Rebulla, Susanna Esposito, Fabio Mosca
Affiliations
- Pediatric Dermatology Unit, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy Pediatric Highly Intensive Care Unit, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy.
- Pediatric Highly Intensive Care Unit, Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy.
- Neonatal Intensive Care Unit, Department of Clinical Science and Community Health, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, University of Milan, Milan, Italy.
- Blood Transfusion Unit, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, Milan, Italy.
PMID: 25572600
PMCID: PMC4289807
DOI: 10.1136/bcr-2014-207364

